Skin biopsies are commonly used in investigating skin diseases. samples are taken using a punch biopsy tool or by surgical excision with the animal under sedation and/or local anaesthetic. If the lesions involve the face or feet, general anaesthesia will be required. The skin samples are investigated using histopathology and special staining, microbial culture, PCR or immunostaining.
1. Punch biopsy
2. Excisional Biopsy
3. Great Dane with immune-mediated Pemphigus Foliaceus
4. Histopathology showing subcorneal pustule
5. Immunofluorescence showing intercellular IgG antibody
